VX2; Hepatic implantation tumor Chemoembolization Angiogenesis inhibitor ( endostatin) Magnetic resonance imaging Diffusion weighted imaging with background suppression; 肝移植瘤;化学栓塞;血管生成抑制剂内皮抑素;磁共振成像;背景信号抑制扩散加权成像;
The results suggest that physicians should monitor patients'kidney health when prescribing this angiogenesis inhibitor. 该研究建议医生在临床使用血管生成抑制剂时需要监控患者的肾脏情况。
Inhibitory Effect of Angiogenesis Inhibitor YH-16 in Combination with Chemoembolization on Rat's Transplanted Hepatoma 血管生成抑制剂YH-16联合化疗栓塞抑制大鼠移植型肝癌的研究
Progress of Angiogenesis Inhibitor in the treatment of Ovarian Cancer 血管生成抑制剂治疗卵巢癌的研究进展
Currently, such angiogenesis inhibitor drugs, including Genentech Inc.'s Avastin, work from the outside of the cell. 目前,包括基因泰克公司的阿瓦斯丁在内的血管生成抑制剂药物的起效是作用于细胞外部。
The Effect of Recombination Angiogenesis Inhibitor Ad-METH-1 on Hypertrophic Scar 重组血管生成抑制剂Ad-METH-1对增生性瘢痕作用的实验研究
Endostatin, the C terminal proteolytic fragment of collagen X ⅷ, is a potent endogenous angiogenesis inhibitor. 内皮抑素为胶原X羧基末端裂解片段,是重要的内源性血管抑制因子。
Objective To explore the expression of brain-specific angiogenesis inhibitor 1 ( BAI1) gene in rectal cancer tissues and its effect on growth and angiogenesis of the tumor. 目的探讨直肠癌组织中脑特异性血管生长抑制因子1(BAI1)基因的表达情况及BAI1对肿瘤血管生成和肿瘤生长的作用。
Objective: The inhibition effect of angiogenesis inhibitor TNP 470 was investigated in a murine malignant ascites model. 目的:研究血管生成抑制剂TNP470对小鼠恶性腹腔积液形成的抑制作用。
Objective: To observe the inhibitive effects of the angiogenesis inhibitor, TNP 470, on the growth and lung metastases of highly lung metastatic salivary adenoid cystic carcinoma ( ACC M) in nude mice, to investigate the mechanisms of TNP 470 against ACC M in vivo. 目的:研究血管生成抑制物TNP-470对肺高转移性涎腺腺样囊性癌(ACC-M)在裸鼠体内生长和转移的抑制作用,探讨其作用机制。
Objective To study the effect of angiogenesis inhibitor TNP-470 on the metastasis of salivary adenoid cystic carcinoma in vivo. 目的观察血管生成抑制剂TNP-470对人涎腺腺样囊性癌肺转移的抑制作用。
Effect of Angiogenesis Inhibitor Nordihydroguaiaretic Acid on Embryo and Ovarian Function in Rat 血管生成抑制剂去甲二氢愈创木酸(NDGA)对大鼠胚胎及卵巢功能影响的初步研究
BACKGROUND& OBJECTIVE: Treating tumor with angiogenesis inhibitor and chemotherapeutic drugs is a research hot spot now. 背景与目的:血管生成抑制剂联合化疗药物治疗肿瘤成为目前研究热点之一。
Experimental study of angiogenesis inhibitor TNP-470 on suppression of tumour growth and microvascular angiogenesis 血管形成抑制剂TNP-470抑制肿瘤生长和微血管形成的实验研究
Angiogenesis inhibitor TNP-470 inhibits the growth of vascular endothelium from hemangioma in vitro 血管生成抑制剂TNP-470抑制血管瘤血管内皮细胞增殖的体外实验研究
BACKGROUND& OBJECTIVE: NK4 is not only an antagonist of hepatocyte growth factor but also an angiogenesis inhibitor. 背景与目的:NK4不仅是肝细胞生长因子的拮抗剂,而且是血管形成的抑制剂。
Effects of angiogenesis inhibitor TNP-470 on mouse bladder cancer 血管形成抑制剂TNP-470对膀胱癌抑制作用的实验研究
Inhibitory effects of angiogenesis inhibitor TNP-470 on growth of a human malignant glioma cell line SHG-44 and its xenografted tumor 血管生成抑制剂TNP-470对人恶性胶质瘤细胞系SHG44及其移植瘤生长的影响
Human angiogenesis inhibitor endostatin gene cloning and expression of pronucleus 血管生成抑制因子人内皮抑素基因的克隆与原核表达
Kringle 1-3 domain is a recently found angiogenesis inhibitor with anti-angiogenesis and anti-tumor activity. 纤溶酶原K13功能区是近年发现的血管生成抑制因子,具有抑制肿瘤生长和转移的活性。
Purpose To synthesize a new antitumor drug 2-methoxyestradiol which is an angiogenesis inhibitor. 目的合成抗肿瘤新药新生血管形成抑制剂2甲氧基雌二醇。
Objective The inhibition effect of angiogenesis inhibitor TNP 470 on tumor growth and metastasis was studied using Lewis lung carcinoma. 目的采用Lewis肺癌来验证血管生成抑制剂TNP-470对肿瘤生长和转移的抑制作用。
In this study, we utilized Celecoxib as angiogenesis inhibitor, Minocycline as matrix metalloproteinase inhibitor to therapy breast cancer bone metastasis nude mouse model, and the result were positive. 我们利用塞莱昔布抑制肿瘤新生血管形成的作用与米诺环素抑制基质金属蛋白酶的作用在动物试验上对乳腺癌骨转移瘤的生长进行了研究,并对其作用的机理进行了初步的探讨。
Objective To observe the inhibitory effect of endogenous angiogenesis inhibitor endostatin on the growth of bladder transitional cell carcinoma. 目的观察内源性血管形成抑制剂(endostatin)对膀胱癌生长的抑制作用。
Method By searching literature, the process and mechanism of angiogenesis were summarized, and diseases induced by angiogenesis and application of angiogenesis inhibitor were introduced. 方法通过检索国外相关领域的文献,对血管形成的过程和调节机制,以及血管形成相关的疾病和血管形成抑制剂在疾病治疗中的应用进行概括介绍。
Objective To introduce the process and mechanism of angiogenesis and application of angiogenesis inhibitor to diseases. 目的介绍血管形成的过程及调节机制,以及血管形成抑制剂在疾病治疗中的应用。
Purpose To investigate the effect of angiogenesis inhibitor ( endostatin) on the proliferation and metastasis of colon cancers in vivo. To explore the role of matrix metalloproteinase-13 ( MMP-13) on angiogenesis in colon cancers. 目的研究内皮抑素对结肠癌增殖和转移的抑制作用,并探讨基质金属蛋白酶13(MMP13)对结肠癌血管生成的作用。
Since the endogenous angiogenesis inhibitor showed highly selective in inhibiting the proliferation of the tumor bed, it was reasonably to be considered the most potential protein drug for anti-angiogenic therapy. 由于内源性血管生成抑制因子显示出抑制瘤床内皮细胞增殖的高度选择性,因此被认为是抗血管生成治疗中最有潜力的药物蛋白质,寻找内源性的血管生成抑制因子成为近年来研究的热点。
Hence, multi-target agents with rational combination of cytotoxic agents and angiogenesis inhibitor have potential application. 因此,兼具传统细胞毒药物与新生血管生成抑制剂效果的多靶点药物具有潜在应用前景。